A preliminary description of the software for a computer-display system is given with special emphasis on the man-machine interaction. This system is intended for a wide variety of biomedical applications. As an example, the methods are applied to the karyotyping of chromosomes. The system is separated into four programming tasks: picture transformations, file maintenance, picture structuring, and display management. Picture structuring is considered as the vehicle for man-machine communication. A prototype data format for pictures, called a picture-form, is developed. Structure operators are defined which manipulate picture-forms to produce new picture-forms. Many of the ideas are taken from the symbolic mathematical laboratory at MIT conceived by Marvin Minsky.
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