September 1964 - Vol. 7 No. 9

September 1964 issue cover image

Features

Research and Advances

A multiuser computation facility for education and research

Present-day computing facilities are limited in their value for scientific research by inability to interact strongly with users. The full power of a research computing instrument should be available at many terminals that give each user the ability to generate, correct and operate any procedure he wishes, either simple or complex. Implementation is described for a small-scale multiuser computer system that permits several users to work independently with the machine, and to obtain satisfactory response using typewriter communication.
Research and Advances

Scheduling meetings with a computer

Computer scheduling of papers as it was developed for the 1960 meeting of the Federation of American Societies for Experimental Biology (FASEB) is described. The FASEB meeting is the largest scientific meeting held in the United States each year. The technique developed for FASEB can be applied to schedule any meeting with parallel sessions.
Research and Advances

A computer analysis method for thermal diffusion in biochemical systems

In the thermal detection of rapid biochemical reactions it is necessary to correct the temperature data for transient heat conduction losses in a cylindrical calorimeter. To handle the complexities arising from varying thermal-relaxation times of concentric insulating layers, a computer program was developed which gives the temperature distribution of the system as a function of radius and time. This distribution is corrected at each step by a subroutine which calculates the instantaneous chemical state of the reaction, as well as the heat produced by this reaction. The program is based on a direct statement of Fourier's law of heat conduction and the chemical rate equation to provide a “bookkeeping law” to follow the reactants and the flow of heat packets, in such a way that the computer continually stores the heat distribution. A computer analysis method is here regarded as one in which the physical laws of a process are used explicitly in the program. Usually this results in bypassing much of the mathematical procedures conventionally used.
Research and Advances

A rapid method for digital filtering

Since much of the computer time spent in time-series analysis is used for multiplications, a minimum multiplication method was devised for digital filtering, with the expectation that it would be useful in the online, real-time analysis of biological data. The filters are constructed from a succession of readily analyzable components in a manner that facilitates cascading. The repertoire of frequency response curves includes relatively good low-pass and band-pass designs. Programs are available for implementing both the synthesis of these filters, and their application on computers whose assemblers allow the definition of recursive macros.

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