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Harvard's Eardrum-Restoring PhonoGraft Enters Commercial Development


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A three-dimensionally printed tympanic membrane.

The researchers designed the PhonoGraft technology to utilize a novel biomaterial-based approach that guides the regeneration of native eardrum tissue.

Credit: Wyss Institute at Harvard University

A biomimetic hearing-restoration device developed by researchers at Harvard University has entered commercial development.

Known as the PhonoGraft, the biocompatible graft is three-dimensionally (3D) printed using a synthetic polymer-based ink system that can replicate the eardrum's circular and radial structure and its sound-conducting mechanical properties and barrier functions.

The device can be implanted to repair a damaged eardrum, helping stimulate the self-healing properties of native eardrum tissue.

Beacon Bio, a startup launched by members of the research team with an exclusive license to commercialize the device, recently was acquired by Desktop Metal Inc. healthcare subsidiary Desktop Health.

The researchers are now seeking clearance for the device from the U.S. Food and Drug Administration.

From Wyss Institute at Harvard
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