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Hybrid 3D-Printing Bioinks Help Repair Knee Cartilage


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Bioprinted material takes the place of damaged cartilege.

Researchers have developed two new hybrid bioinks that can be used to 3D-print a replacement for damaged knee cartilage.

Credit: Alexmit/Depositphotos

Researchers at the Wake Forest Institute for Regenerative Medicine (WFIRM) have engineered two new three-dimensional (3D) printing hybrid bioinks that can be used to print a replacement for damaged knee cartilage.

The WFIRM team used the Integrated Tissue and Organ Printing System, which can print complex tissues, as well as two bioinks, to print a knee’s fibrocartilage tissue layer by layer.

One bioink is a composite gellan gum and fibrinogen ink that encourages the patient’s cells to repopulate, while the other is a silk fibroin methacrylate to provide structural strength and flexibility to the printed material.

Laboratory tests indicated cells could proliferate in the new material and stay viable, while the structure itself remained biomechanically sound.

From New Atlas
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