Researchers at Italy's University of Modena and Reggio Emilia (UniMoRE), the CNR-Institute for Photonics and Nanotechnologies, Delft University of Technology, and University Medical Center Rotterdam have developed a plug-and-play lens that streamlines adaptive optics for microscopy.
The team fabricated the lens from extremely thin, liquid-filled glass that bends into a desired shape, via computer-controlled actuators. The lens transmits light, while the database online nonlinear extremum-seeker algorithm operates the actuators to perform adaptive optics correction. The researchers applied the device to the objective lens of a commercial multiphoton microscope while conducting calcium imaging on the brains of living mice, producing quality results within a few hours.
A paper describing their work is published in Optics Letters.
"Our new device could also be applied in other fields such as free space optics communications, where it could increase data connection rates and bring data connections to remote and isolated areas," says UniMoRE's Paolo Pozzi.
From The Optical Society
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Abstracts Copyright © 2020 SmithBucklin, Washington, DC, USA
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