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CRISPR Gene Editing Produces Unwanted DNA Deletions

Human embryonic stem cell

Gene-editing experiments with human embryonic stem cells revealed the imprecision of the CRISPR-Cas9 system.

Credit: Annie Cavanagh via Wellcome

Researchers have embraced CRISPR gene-editing as a method for altering genomes, but some are cautioning that unwanted DNA changes may slip by undetected.

From Nature
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