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ACM TechNews

Forecasting the Evolution of Cancer


Stages of tumor development.

Researchers at Queen Mary University of London (QMUL), University College London, Barts Cancer Institute, and the Institute of Cancer Research have collaborated on a computer model that predicts how tumors will develop.

Credit: Van-Tinh Nguyen

A computer model that predicts how tumors will develop has been created by researchers at Queen Mary University of London (QMUL), University College London, Barts Cancer Institute, and the Institute of Cancer Research, all in the U.K.

Their study sought to find a way of interpreting the genetic sequences of cancerous cells by using hidden driver mutations.

The model employs this genetic data in conjunction with defined algorithms to forecast changes that may happen as the tumor progresses.

The next step for the team is to confirm the accuracy of the system's predictions by testing it in pre-clinical models and analyzing tumor samples of patients under long-term surveillance.

"It would be a great advantage to know if a tumor is going to change in a certain way and so be able to administer the most effective treatment in light of the prediction," says QMUL's Trevor Graham.

From Queen Mary University of London
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